Medicaid-dependent healthcare companies are experiencing their worst trading sessions in history as the legislation projects 12-17 million Americans will lose health coverage through new work requirements and eligibility restrictions. Centene Corporation plummeted 38-40% in a single session after withdrawing 2025 guidance and citing $1.8 billion in revenue reductions, marking the worst decline in company history. Meanwhile, diversified insurers with limited government program exposure are demonstrating remarkable resilience, highlighting the importance of business model analysis in the new regulatory environment.